Panel softens cancer gene test warning
نویسندگان
چکیده
منابع مشابه
Gene panel testing for hereditary breast cancer.
Inherited predisposition to breast cancer is explained only in part by mutations in the BRCA1 and BRCA2 genes. Most families with an apparent familial clustering of breast cancer who are investigated through Australia's network of genetic services and familial cancer centres do not have mutations in either of these genes. More recently, additional breast cancer predisposition genes, such as PAL...
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Douglas F. Easton, Ph.D., Paul D.P. Pharoah, Ph.D., Antonis C. Antoniou, Ph.D., Marc Tischkowitz, M.D., Ph.D., Sean V. Tavtigian, Ph.D., Katherine L. Nathanson, M.D., Peter Devilee, Ph.D., Alfons Meindl, Ph.D., Fergus J. Couch, Ph.D., Melissa Southey, Ph.D., David E. Goldgar, Ph.D., D. Gareth R. Evans, M.D., Georgia Chenevix‐Trench, Ph.D., Nazneen Rahman, M.D., Ph.D., Mark Robson, M.D., Susan M...
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abstract This paper studies the asymptotic covariance estimation associated with the LIML estimator for large-T dynamic panel structural equations. The proposed simple estimation method is based on the fixed-N or large Kasymptotics relating to the number of backward-filtered instruments. We demonstrate the resulting t-Test which also does not need asymptotic bias correction works well with the ...
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ژورنال
عنوان ژورنال: Nature
سال: 1996
ISSN: 0028-0836,1476-4687
DOI: 10.1038/380573a0